The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2019
Filed:
Nov. 14, 2016
Northwestern University, Evanston, IL (US);
King Abdulaziz City for Science and Technology, Riyadh, SA;
Karel J. Hartlieb, Evanston, IL (US);
James M. Holcroft, Newcastle upon Tyne, GB;
James Fraser Stoddart, Evanston, IL (US);
Daniel Patrick Ferris, Evanston, IL (US);
Northwestern University, Evanston, IL (US);
King Abdulaziz City for Science and Technology, Riyadh, SA;
Abstract
Pharmaceutical complexes composed of drug molecules entrapped in cyclodextrin-based MOFs (CD-MOFs) are provided. Pharmaceutical tablets incorporating crystals of the pharmaceutical complexes for oral administration to a patient are also provided. In addition, methods of making the pharmaceutical complexes using anion-exchange reactions and methods of making the pharmaceutical complexes based on the co-crystallization of the drug molecules with cyclodextrin are provided. The pharmaceutical complexes include a CD-MOF and deprotonated drug anions associated with alkali metal cations in the CD-MOF superstructure.