The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2019
Filed:
Jul. 18, 2018
Applicants:
New York University, New York, NY (US);
New York University IN Abu Dhabi Corporation, Abu Dhabi, AE;
Inventors:
Sunil Kumar, New York, NY (US);
Andrew D. Hamilton, New York, NY (US);
Mazin Magzoub, Abu Dhabi, AE;
Sarah Hassan, Abu Dhabi, AE;
Assignees:
New York University, New York, NY (US);
New York University in Abu Dhabi Corporation, Abu Dhabi, AE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/444 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/444 (2013.01); A61P 35/00 (2018.01);
Abstract
The invention relates to oligopyridylamide alpha-helix mimetic compounds and their use to inhibit p53 aggregation and restore its tumor suppressor function for treating diseases, e.g., cancers, associated with p53 mutations, e.g., R248W p53 mutation.