The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2019

Filed:

Aug. 04, 2016
Applicant:

Aequus Pharmaceuticals Inc., Vancouver, CA;

Inventors:

Fotios M. Plakogiannis, Whitestone, NY (US);

Donald McAfee, Pt. Roberts, WA (US);

Tamanna Lather, Jersey City, NJ (US);

Marina Borovinskaya, East Brunswick, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4415 (2006.01); A61K 31/435 (2006.01); A61K 9/00 (2006.01); A61K 31/4402 (2006.01); A61K 9/06 (2006.01); A61K 47/10 (2017.01); A61K 47/24 (2006.01); A61K 47/38 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4415 (2013.01); A61K 9/0014 (2013.01); A61K 9/06 (2013.01); A61K 31/4402 (2013.01); A61K 47/10 (2013.01); A61K 47/24 (2013.01); A61K 47/38 (2013.01);
Abstract

Pharmaceutical compositions for simultaneous transdermal delivery of Doxylamine and Pyridoxine comprising Doxylamine or its salts, Pyridoxine or its salts or its active metabolites and a vehicle system wherein pharmaceutical compositions are liquid formulations, semisolid formulations and polymer matrices. Further pharmaceutical compositions can be incorporated into transdermal delivery systems or transdermal patches. The invention provides a method for treatment of nausea and vomiting in general, and for pregnant women in particular by continuous and simultaneous transdermal delivery of Doxylamine and Pyridoxine. This is to be accomplished through topical application of pharmaceutical compositions or by application of a transdermal delivery system or transdermal patch to the surface of the skin wherein the duration of application is once in a day, once every two days, once every three days, once every four days, once every five days, once every six days, or once in a week.


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