The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2019

Filed:

Jul. 02, 2015
Applicant:

Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd., Shijiazhuang, CN;

Inventors:

Chunlei Li, Shijiazhuang, CN;

Yanhui Li, Shijiazhuang, CN;

Min Liang, Shijiazhuang, CN;

Caixia Wang, Shijiazhuang, CN;

Yajuan Wang, Shijiazhuang, CN;

Shixia Wang, Shijiazhuang, CN;

Dongjian Chen, Shijiazhuang, CN;

Yongfeng Li, Shijiazhuang, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); B82Y 5/00 (2011.01); A61K 31/337 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5169 (2013.01); A61K 31/337 (2013.01); B82Y 5/00 (2013.01);
Abstract

Purified therapeutic nanoparticles are provided herein. Such nanoparticles comprise an active pharmaceutical ingredient and human serum albumin, wherein the weight ratio of human serum albumin to the active ingredient in the therapeutic nanoparticles is from 0.01:1 to 1:1, and wherein the nanoparticles are substantially free of free human serum albumin that is not incorporated in the nanoparticles. The present disclosure also provides pharmaceutical compositions that comprise the purified therapeutic nanoparticles and are also substantially free of free human serum albumin. Methods for preparing and using the purified therapeutic nanoparticles and compositions thereof are also provided.


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