The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2019
Filed:
Jan. 29, 2016
The Regents of the University of California, Oakland, CA (US);
Charite-universitatsmedizin Berlin, Berlin, DE;
Mt. Sinai Hospital, Toronto, CA;
Michael Demetriou, Irvine, CA (US);
Alexander Brandt, Berlin, DE;
Friedmann Paul, Berlin, DE;
James Dennis, Toronto, CA;
The Regents of the University of California, Oakland, CA (US);
Charite-Universitatsmedizin Berlin, Berlin, DE;
Mt. Sinai Hospital, Toronto, CA;
Abstract
The invention provides the art with a powerful diagnostic method of distinguishing relapse-remitting MS subjects from progressive MS subjects, based on the measurement of serum concentrations of N-acetylglucosamine (GlcNAc,), for the first time enabling rapid diagnosis of the progressive form of MS. GlcNAc serum concentration can also be used to assess neurodegenerative status and MS progression in subjects suffering from MS or other neurological conditions. The methods of the invention also allow for the identification of new therapeutics for MS and other neurological conditions and also enables the personalized efficacy assessment of a potential therapy for an MS subject.