The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2019
Filed:
Feb. 09, 2018
Applicant:
The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);
Inventors:
Jason Holder, Swampscott, MA (US);
Connor McBrine, Somerville, MA (US);
Miles Rogers, Boston, MA (US);
Nicole Billings, Framingham, MA (US);
Sarah Gruska, Cambridge, MA (US);
Lucas Tilley, Medford, MA (US);
Assignee:
The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/70 (2006.01); C12N 15/11 (2006.01); C12N 7/00 (2006.01); C12N 9/96 (2006.01); C12N 9/22 (2006.01); C12N 9/02 (2006.01); C07K 14/005 (2006.01); C12Q 1/70 (2006.01); C12N 15/113 (2010.01); C12N 15/86 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 15/70 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); C12N 9/0069 (2013.01); C12N 9/22 (2013.01); C12N 9/96 (2013.01); C12N 15/11 (2013.01); C12N 15/1131 (2013.01); C12N 15/86 (2013.01); C12Q 1/70 (2013.01); C12N 15/902 (2013.01); C12N 2310/20 (2017.05); C12N 2795/10221 (2013.01); C12N 2795/10243 (2013.01); C12N 2800/80 (2013.01);
Abstract
The present disclosure provides methods and kits for generating recombinant bacteriophage genomes. Specifically, the present technology provides methods of integrating a heterologous nucleic acid sequence into a bacteriophage DNA genome, and isolating recombinant bacteriophages that express the heterologous nucleic acid sequence.