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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10494638 B1

PDFFull Text
Date of Patent:
Dec. 03, 2019

Filed:

Feb. 09, 2018

Bacteriophage recombination followed by blockage of non-recombinant bacteriophage replication

Applicant:

The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);

Inventors:

Jason Holder, Swampscott, MA (US);

Connor McBrine, Somerville, MA (US);

Miles Rogers, Boston, MA (US);

Nicole Billings, Framingham, MA (US);

Sarah Gruska, Cambridge, MA (US);

Lucas Tilley, Medford, MA (US);

Assignee:

The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);

Attorneys:

Foley & Lardner LLP

Christopher J. McKenna

Primary Examiner:

Nancy A Treptow

Int. Cl.
CPC ...
C12N 15/70 (2006.01); C12N 15/11 (2006.01); C12N 7/00 (2006.01); C12N 9/96 (2006.01); C12N 9/22 (2006.01); C12N 9/02 (2006.01); C07K 14/005 (2006.01); C12Q 1/70 (2006.01); C12N 15/113 (2010.01); C12N 15/86 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 15/70 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); C12N 9/0069 (2013.01); C12N 9/22 (2013.01); C12N 9/96 (2013.01); C12N 15/11 (2013.01); C12N 15/1131 (2013.01); C12N 15/86 (2013.01); C12Q 1/70 (2013.01); C12N 15/902 (2013.01); C12N 2310/20 (2017.05); C12N 2795/10221 (2013.01); C12N 2795/10243 (2013.01); C12N 2800/80 (2013.01);
Abstract

The present disclosure provides methods and kits for generating recombinant bacteriophage genomes. Specifically, the present technology provides methods of integrating a heterologous nucleic acid sequence into a bacteriophage DNA genome, and isolating recombinant bacteriophages that express the heterologous nucleic acid sequence.

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Holder, Jason. (2019). Bacteriophage recombination followed by blockage of non-recombinant bacteriophage replication (U.S. Patent No. 10494638). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10494638

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