The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2019
Filed:
May. 04, 2017
Applicant:
Canadian Blood Services, Ottawa, CA;
Inventors:
William Peter Sheffield, Hamilton, CA;
David Apraku Donkor, Hamilton, CA;
Assignee:
CANADIAN BLOOD SERVICES, Ottawa, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61K 49/00 (2006.01); G01N 33/86 (2006.01); C12N 15/115 (2010.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); A61K 49/0004 (2013.01); C12N 15/115 (2013.01); C12Y 304/21027 (2013.01); G01N 33/86 (2013.01); C12N 2310/16 (2013.01); G01N 2333/96452 (2013.01);
Abstract
The present disclosure concerns aptamers of formula (I) capable of specifically binding to Factor XIa. The aptamers can be used to prevent, treat or alleviate the symptoms of thrombosis. The aptamers can also be used to detect Factor XIa in a sample and/or purify Factor XIa from a sample. The aptamers can further be used to identity putative therapeutic agents for the prevention, treatment or alleviation of symptoms associated with thrombosis.