The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2019
Filed:
Mar. 24, 2017
Yiwei Huang, Erlangen, DE;
Divya Khandige Sharma, Bangalore/Karnataka, IN;
Ragavendar MS, Bangalore, IN;
Nivedita Mitra, Bangalore, IN;
Ramya Vutukuru, Karnataka, IN;
Yiwei Huang, Erlangen, DE;
Divya Khandige Sharma, Bangalore/Karnataka, IN;
Ragavendar Ms, Bangalore, IN;
Nivedita Mitra, Bangalore, IN;
Ramya Vutukuru, Karnataka, IN;
Siemens Healthcare GmbH, Erlangen, DE;
Abstract
A method and apparatus for enrichment and detection of low abundance pathogens are provided. The method includes adding one or more proteins containing pathogen binding domains to the sample. The sample is incubated to form a complex thereby. The complex is separated from the sample, and an apparatus is provided for enriching pathogen DNA that achieves pathogen detection levels as low as 1 cfu/ml. The method further includes adding a lysis buffer to the separated complex and incubating to form a mixture. A buffer containing guanidine thiocyanate is added to the mixture. The mixture is connected with a matrix to form a bound entity, and the bound entity is separated from the mixture.