The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 03, 2019

Filed:

Feb. 12, 2008
Applicants:

James W. Edinger, Belford, NJ (US);

Robert J. Hariri, Florham Park, NJ (US);

Jia-lun Wang, Cherry Hill, NJ (US);

Qian YE, Livingston, NJ (US);

Marian Pereira, Cranford, NJ (US);

Sascha Dawn Abramson, Hillsborough, NJ (US);

Kristen S. Labazzo, Springfield, NJ (US);

Inventors:

James W. Edinger, Belford, NJ (US);

Robert J. Hariri, Florham Park, NJ (US);

Jia-Lun Wang, Cherry Hill, NJ (US);

Qian Ye, Livingston, NJ (US);

Marian Pereira, Cranford, NJ (US);

Sascha Dawn Abramson, Hillsborough, NJ (US);

Kristen S. Labazzo, Springfield, NJ (US);

Assignee:

CELULARITY, INC., Warren, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/073 (2010.01); C12N 5/071 (2010.01); A01K 67/027 (2006.01); C12N 5/074 (2010.01); C12N 5/077 (2010.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 5/067 (2013.01); A01K 67/0271 (2013.01); C12N 5/0605 (2013.01); C12N 5/0607 (2013.01); C12N 5/0655 (2013.01); A01K 2267/0337 (2013.01); A61K 2035/128 (2013.01); C12N 2500/30 (2013.01); C12N 2500/36 (2013.01); C12N 2500/62 (2013.01); C12N 2501/15 (2013.01); C12N 2501/999 (2013.01); C12N 2506/02 (2013.01); C12N 2506/03 (2013.01); C12N 2533/32 (2013.01); C12N 2533/40 (2013.01); C12N 2533/74 (2013.01);
Abstract

Provided herein are methods and compositions for the production of hepatocytes from placenta stem cells. Further provided herein is the use of such hepatocytes in the treatment of, and intervention in, for example, trauma, inflammation, and degenerative disorders of the liver. Also provided herein are compositions and methods relating to combinations of nanofibrous scaffolds and adherent placental stem cells and methods of using the same in cartilage repair. Finally, provided herein are compositions and methods relating to nonadherent, CD34CD45stem cells from placenta.


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