The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 03, 2019

Filed:

Mar. 25, 2015
Applicant:

University of Utah Research Foundation, Salt Lake City, UT (US);

Inventors:

Carol Lim, Salt Lake City, UT (US);

Benjamin J. Bruno, Salt Lake City, UT (US);

Geoffrey D. Miller, Salt Lake City, UT (US);

Andrew S. Dixon, Salt Lake City, UT (US);

Assignee:

UNIVERSITY OF UTAH RESEARCH FOUNDATION, Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 14/82 (2006.01); A61K 31/5025 (2006.01); A61K 31/506 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
C07K 14/82 (2013.01); A61K 31/506 (2013.01); A61K 31/5025 (2013.01); A61K 38/17 (2013.01); A61K 38/00 (2013.01);
Abstract

In one aspect, the invention relates to peptides comprising the Bcr-Abl coiled-coil oligomerization domain and an alpha helix stabilizing moiety, mutant forms thereof, truncated forms thereof, derivatives thereof, and related peptides, which are useful as inhibitors of the Bcr-Abl chimeric protein; pharmaceutical compositions comprising the compounds; and methods of treating hyperproliferative disorders associated with Bcr-Abl using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.


Find Patent Forward Citations

Loading…