The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 03, 2019

Filed:

Jul. 21, 2016
Applicant:

Guangzhou Maxinovel Pharmaceuticals Co., Ltd., Guangzhou, CN;

Inventors:

Zusheng Xu, Shanghai, CN;

Nong Zhang, Shanghai, CN;

Tinghan Wang, Shanghai, CN;

Qingrui Sun, Shanghai, CN;

Yuguang Wang, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); A61K 31/519 (2006.01); C07D 471/04 (2006.01); A61K 9/127 (2006.01); A61K 31/517 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); C07D 495/14 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61K 9/127 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 471/04 (2013.01); C07D 495/14 (2013.01);
Abstract

Disclosed area fused ring pyrimidine compound, and an intermediate, a preparation method, a composition and a use thereof. The fused ring pyrimidine compound is a compound as shown in formula I, a tautomer, an enantiomer, a diastereoisomer, a pharmaceutically acceptable salt, a metabolite, a metabolic precursor or a prodrug thereof, wherein the above-mentioned compound is used for the preparation of a medicine for preventing, remitting or treating one or more of immune system diseases, autoimmune diseases, cell proliferative diseases, allergic disorders and cardiovascular diseases, and the compound has a strong inhibitory effect on the Janues kinase, FGFR kinase, FLT3 kinase and Src family kinase.


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