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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10494364 B1

PDFFull Text
Date of Patent:
Dec. 03, 2019

Filed:

Aug. 26, 2016

Cathepsin k inhibitors and application thereof

Applicant:

Sunshine Lake Pharma Co., Ltd., Dongguan, Guangdong, CN;

Inventors:

Xiaojun Wang, Dongguan, CN;

Pingjian Zhou, Dongguan, CN;

Chuanwen Yang, Dongguan, CN;

Changwei Huang, Dongguan, CN;

Shaohui Xiong, Dongguan, CN;

Yingjun Zhang, Dongguan, CN;

Jiancun Zhang, Dongguan, CN;

Assignees:

SUNSHIN LAKE PHARMA CO., LTD, Dongguan, Guangdong, CN;

NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED, Wanchai, HK;

Attorney:

Kam Wah Law

Primary Examiner:

Zinna Northington Davis

Int. Cl.
CPC ...
C07D 407/10 (2006.01); A61K 31/343 (2006.01); A61K 31/351 (2006.01); A61K 31/357 (2006.01); A61K 31/36 (2006.01); A61K 31/38 (2006.01); A61K 31/381 (2006.01); A61K 31/382 (2006.01); A61K 31/39 (2006.01); A61K 31/397 (2006.01); A61K 31/41 (2006.01); A61K 31/4178 (2006.01); A61K 31/4192 (2006.01); A61K 31/4196 (2006.01); A61K 31/422 (2006.01); A61K 31/423 (2006.01); A61K 31/4245 (2006.01); A61K 31/427 (2006.01); A61K 31/4355 (2006.01); A61K 31/437 (2006.01); A61K 31/443 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); A61K 45/06 (2006.01); C07D 307/85 (2006.01); C07D 405/10 (2006.01); C07D 407/12 (2006.01); C07D 407/14 (2006.01); C07D 409/10 (2006.01); C07D 411/10 (2006.01); C07D 413/10 (2006.01); C07D 413/14 (2006.01); C07D 417/10 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 493/04 (2006.01);
U.S. Cl.
CPC ...
C07D 407/10 (2013.01); A61K 31/343 (2013.01); A61K 31/351 (2013.01); A61K 31/357 (2013.01); A61K 31/36 (2013.01); A61K 31/38 (2013.01); A61K 31/381 (2013.01); A61K 31/382 (2013.01); A61K 31/39 (2013.01); A61K 31/397 (2013.01); A61K 31/41 (2013.01); A61K 31/4178 (2013.01); A61K 31/4192 (2013.01); A61K 31/4196 (2013.01); A61K 31/422 (2013.01); A61K 31/423 (2013.01); A61K 31/427 (2013.01); A61K 31/4245 (2013.01); A61K 31/437 (2013.01); A61K 31/4355 (2013.01); A61K 31/443 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 45/06 (2013.01); C07D 307/85 (2013.01); C07D 405/10 (2013.01); C07D 407/12 (2013.01); C07D 407/14 (2013.01); C07D 409/10 (2013.01); C07D 411/10 (2013.01); C07D 413/10 (2013.01); C07D 413/14 (2013.01); C07D 417/10 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 493/04 (2013.01);
Abstract

The invention relates to capthepsin K inhibitors and uses thereof, specifically relates to a class of compounds having the formula (I) which are used for treating or preventing cathepsin dependent diseases or conditions, specifically, wherein the cathepsin is capthepsin K. The compounds and compositions thereof can be used as bone resorption inhibitors for the treatment of associated diseases.

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