The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 03, 2019

Filed:

Mar. 08, 2017
Applicant:

Netherlands Translational Research Center B.v., AG Oss, NL;

Inventors:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 233/32 (2006.01); A61P 37/00 (2006.01); A61P 33/00 (2006.01); A61P 25/28 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); A61P 25/28 (2018.01); A61P 31/12 (2018.01); A61P 33/00 (2018.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01); C07D 233/32 (2013.01);
Abstract

A compound of Formula I: or pharmaceutically acceptable enantiomers, or salts thereof. The present invention also relates to the use of compounds of Formula (I) as selective inhibitors of indoleamine 2,3-dioxygenase. The invention also relates to the use of the compounds of Formula (I) for the treatment or prevention of diseases cancer, infections, central nervous system disease or disorder, and immune-related disorders, either as a single agent or in combination with other therapies.


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