The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2019
Filed:
May. 12, 2017
Sung Kyun Biotech Co., Ltd., Gyeonggi-do, KR;
Hyun Suk Kim, Seoul, KR;
Kimoon Park, Gyeonggi-do, KR;
Min-hyuk Bang, Jeollabuk-do, KR;
Hee-Jin Yang, Seoul, KR;
Yun Mi Lee, Seoul, KR;
Ki Hyun Kim, Gyeongsangnam-do, KR;
SUNG KYUN BIOTECH CO., LTD., , KR;
Abstract
The present disclosure relates to a compound having the activity of promoting osteoblast differentiation and inhibiting adipocyte differentiation and a preparation method thereof. The novel compound of the present disclosure increases the expression of the gene ALP involved in the differentiation of osteoblasts, regulates expression of the genes PPARγ, aP2 and CD36 involved in the differentiation of adipocytes, increases bone mineral density (BMD) in an ovariectomized osteoporosis animal model and decreases adipocytes in the bone marrow. Therefore, it can be used as an active ingredient of a medication or a health functional food useful for metabolic bone disease or obesity.