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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10494333 B1

PDFFull Text
Date of Patent:
Dec. 03, 2019

Filed:

Jul. 23, 2016

Compound having blt inhibitory activity and composition, for preventing or treating inflammatory diseases, comprising same as active ingredient

Applicants:

Dongguk University Industry-academic Cooperation Foundation, Seoul, KR;

Korea University Research and Business Foundation, Seoul, KR;

Inventors:

Yongseok Choi, Goyang-si, KR;

Jae-Hong Kim, Seongnam-si, KR;

Kyeong Lee, Goyang-si, KR;

Hyo-Kyung Han, Seoul, KR;

Jun Dong Wei, Seoul, KR;

Jinsun Kwon, Yongin-si, KR;

Ja-Il Goo, Seoul, KR;

Assignees:

DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, Seoul, KR;

KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, Seoul, KR;

Attorney:

Lucas & Mercanti, LLP

Primary Examiner:

Paul V Ward

Int. Cl.
CPC ...
C07D 295/205 (2006.01); C07C 311/21 (2006.01); C07C 233/07 (2006.01); C07C 233/88 (2006.01); C07C 235/34 (2006.01); C07C 237/42 (2006.01); C07C 311/16 (2006.01); C07D 295/192 (2006.01); A61P 11/06 (2006.01); A61P 35/00 (2006.01); C07C 275/32 (2006.01); C07D 257/04 (2006.01); C07D 295/185 (2006.01); C07C 233/51 (2006.01); C07D 213/56 (2006.01); C07D 211/06 (2006.01); C07D 241/04 (2006.01); C07D 265/30 (2006.01);
U.S. Cl.
CPC ...
C07C 311/21 (2013.01); A61P 11/06 (2018.01); A61P 35/00 (2018.01); C07C 233/07 (2013.01); C07C 233/51 (2013.01); C07C 233/88 (2013.01); C07C 235/34 (2013.01); C07C 237/42 (2013.01); C07C 275/32 (2013.01); C07C 311/16 (2013.01); C07D 211/06 (2013.01); C07D 213/56 (2013.01); C07D 241/04 (2013.01); C07D 257/04 (2013.01); C07D 265/30 (2013.01); C07D 295/185 (2013.01); C07D 295/192 (2013.01); C07D 295/205 (2013.01);
Abstract

The present invention relates to a novel compound showing leukotriene B4 receptor 2 (BLT2) inhibitory activity and a pharmaceutical composition, for preventing or treating inflammatory diseases, having same as an active ingredient. The inventors identified a novel compound containing BTL2 inhibitory activity, and experimentally confirmed that the present novel compound had an excellent effect on the enhancement of the cancer cell death, on the inhibition of the metastasis and chemotactic mobility, and on the anti-asthma activity. Therefore, the present novel compound can be used as a very effective pharmaceutical component for treating the inflammatory-related diseases.

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