The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2019
Filed:
Sep. 09, 2015
Applicant:
The University of Iowa Research Foundation, Iowa City, IA (US);
Inventors:
Jack T. Stapleton, Iowa City, IA (US);
Nirjal Bhattarai, Coralville, IA (US);
James McLinden, Coralville, IA (US);
Jinhau Xiang, Iowa City, IA (US);
Bev Davidson, Philadelphia, PA (US);
Assignee:
THE UNIVERSITY OF IOWA RESEARCH FOUNDATION, Iowa City, IA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 39/12 (2006.01); C12N 15/117 (2010.01); C07K 14/08 (2006.01); C07K 14/18 (2006.01); C07K 14/47 (2006.01); C12N 7/04 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); C07K 14/08 (2013.01); C07K 14/1833 (2013.01); C07K 14/473 (2013.01); C12N 7/04 (2013.01); C12N 15/117 (2013.01); C12N 2310/17 (2013.01); C12N 2330/50 (2013.01); C12N 2760/18711 (2013.01); C12N 2770/24111 (2013.01); C12N 2770/24211 (2013.01);
Abstract
The disclosure provides compositions and methods involving viral RNA segments for use in modulating immune responses, including inhibition inflammation related to pathogenic T-cell activation. In addition, modification of the viral sequences responsible for modulating immune response provides for improved vaccine formulations.