logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10493084 B1

PDFFull Text
Date of Patent:
Dec. 03, 2019

Filed:

Jan. 09, 2019

Adjunctive therapy with 25-hydroxyvitamin d and articles therefor

Applicant:

Opko Ireland Global Holdings, Ltd., Grand Cayman, KY;

Inventors:

P. Martin Petkovich, Kingston, CA;

Joel Z. Melnick, Evanston, IL (US);

Jay A. White, Newmarket, CA;

Samir P. Tabash, Whitby, CA;

Charles W. Bishop, Miami Beach, FL (US);

Susan Peers, Toronto, CA;

Stephen A. Strugnell, Bay Harbor Islands, FL (US);

Assignee:

OPKO IRELAND GLOBAL HOLDINGS, LTD., Grand Cayman, KY;

Attorney:

Marshall, Gerstein & Borun LLP

Primary Examiner:

Aradhana Sasan

Assistant Examiner:

Quanglong N Truong

Int. Cl.
CPC ...
A61K 31/593 (2006.01); A61K 31/592 (2006.01); A61K 9/00 (2006.01); A61K 47/26 (2006.01); A61K 9/48 (2006.01); A61K 31/675 (2006.01); A61K 31/135 (2006.01); A61K 31/663 (2006.01); A61K 47/44 (2017.01); A61K 31/137 (2006.01); A61K 45/06 (2006.01); A61K 47/06 (2006.01); A61K 47/14 (2017.01); A61K 47/38 (2006.01);
U.S. Cl.
CPC ...
A61K 31/593 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 9/4825 (2013.01); A61K 9/4875 (2013.01); A61K 31/135 (2013.01); A61K 31/137 (2013.01); A61K 31/592 (2013.01); A61K 31/663 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01); A61K 47/06 (2013.01); A61K 47/14 (2013.01); A61K 47/26 (2013.01); A61K 47/38 (2013.01); A61K 47/44 (2013.01);
Abstract

Methods, compositions, and kits for adjunctive therapy using 25-hydroxyvitamin D are disclosed. The 25-hydroxyvitamin D may be administered with an agent that increases the risk of hypocalcemia, such as cinacalcet or a salt thereof, and/or an anticancer agent. The adjunctive therapy is effective to treat and prevent iatrogenic hypocalcemia and/or secondary hyperparathyroidism, as well as delay cancer progression and the time to a post-treatment skeletal related event.

Find Patent Forward Citations

Loading…