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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10493071 B1

PDFFull Text
Date of Patent:
Dec. 03, 2019

Filed:

May. 30, 2017

Use of pyrroloquinoline compounds to kill clinically latent microorganisms

Applicant:

Helperby Therapeutics Limited, North Yorks, GB;

Inventors:

Petra Helga Beck, Surrey, GB;

Marc Barry Brown, Surrey, GB;

David Edward Clark, Essex, GB;

Anthony Coates, London, GB;

Hazel Joan Dyke, Essex, GB;

Yanmin Hu, London, GB;

Derek John Londesbrough, Sunderland, GB;

Keith Mills, Hertfordshire, GB;

Thomas David Pallin, Essex, GB;

Gary Patrick Reid, Sunderland, GB;

Gerlinda Stoddart, Denham, GB;

Assignee:

HELPERBY THERAPEUTICS LIMITED, Selby, North Yorks, GB;

Attorney:

Sughrue Mion, PLLC

Primary Examiner:

Bethany P Barham

Assistant Examiner:

Barbara S Frazier

Int. Cl.
CPC ...
A61K 31/4745 (2006.01); A61K 31/4439 (2006.01); C07D 471/04 (2006.01); A61K 31/4709 (2006.01); A61L 2/00 (2006.01); A01N 43/90 (2006.01); A61K 31/43 (2006.01); A61K 31/4706 (2006.01); A61K 31/4725 (2006.01); A61K 31/496 (2006.01); A61K 31/497 (2006.01); A61K 31/546 (2006.01); A61K 31/7052 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4745 (2013.01); A61K 31/4439 (2013.01); A61K 31/4709 (2013.01); A61L 2/0088 (2013.01); C07D 471/04 (2013.01); A01N 43/90 (2013.01); A61K 31/43 (2013.01); A61K 31/4706 (2013.01); A61K 31/4725 (2013.01); A61K 31/496 (2013.01); A61K 31/497 (2013.01); A61K 31/546 (2013.01); A61K 31/7052 (2013.01); Y02A 50/401 (2018.01); Y02A 50/404 (2018.01); Y02A 50/406 (2018.01); Y02A 50/411 (2018.01); Y02A 50/469 (2018.01); Y02A 50/473 (2018.01); Y02A 50/475 (2018.01); Y02A 50/478 (2018.01); Y02A 50/479 (2018.01); Y02A 50/481 (2018.01); Y02A 50/483 (2018.01);
Abstract

There is provided the use of compounds of formula I wherein R, R, Rand X have meanings given in the description, for the preparation of a medicament for killing clinically latent microorganisms. There is also provided the use of compounds of formula I for treating microbial infections, as well as certain compounds of formula I per se.

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