The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2019
Filed:
Jun. 28, 2017
Applicant:
Viiv Healthcare Uk (No. 5) Limited, Brentford, Middlesex, GB;
Inventors:
Jie Chen, Wallingford, CT (US);
Nicholas A. Meanwell, Wallingford, CT (US);
Alicia Regueiro-Ren, Wallingford, CT (US);
Sing-Yuen Sit, Wallingford, CT (US);
Jacob Swidorski, Wallingford, CT (US);
Yan Chen, Wallingford, CT (US);
Assignee:
ViiV HEALTHCARE UK (NO. 5) LIMITED, Brentford, Middlesex, GB;
Primary Examiner:
Int. Cl.
CPC ...
C07D 217/06 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 405/12 (2006.01); C07D 407/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 453/00 (2006.01); C07D 471/04 (2006.01); C07D 471/08 (2006.01); C07D 473/28 (2006.01); C07D 487/04 (2006.01); C07D 487/08 (2006.01); C07D 491/056 (2006.01); C07D 495/04 (2006.01); A61K 31/4725 (2006.01); A61K 31/496 (2006.01); A61K 31/522 (2006.01); A61K 31/53 (2006.01); A61K 31/5365 (2006.01); A61K 31/54 (2006.01); A61K 45/06 (2006.01); A61P 31/18 (2006.01); A61K 31/541 (2006.01); C07D 417/14 (2006.01); A61K 31/4748 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4725 (2013.01); A61K 31/4748 (2013.01); A61K 31/496 (2013.01); A61K 31/522 (2013.01); A61K 31/53 (2013.01); A61K 31/5365 (2013.01); A61K 31/541 (2013.01); A61K 45/06 (2013.01); A61P 31/18 (2018.01); C07D 217/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/12 (2013.01); C07D 407/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 453/00 (2013.01); C07D 471/04 (2013.01); C07D 471/08 (2013.01); C07D 473/28 (2013.01); C07D 487/04 (2013.01); C07D 487/08 (2013.01); C07D 491/056 (2013.01); C07D 495/04 (2013.01);
Abstract
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, azadecaline derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formula I: These compounds are useful for the treatment of HIV and AIDS.