The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 03, 2019

Filed:

Sep. 21, 2017
Applicant:

Hong Kong Baptist University, Hong Kong, HK;

Inventors:

Hongjie Zhang, Hong Kong, HK;

Man Shing Ricky Wong, Hong Kong, HK;

Lei Guo, Hong Kong, HK;

Siu Wai Tsang, Hong Kong, HK;

Kanglun Liu, Hong Kong, HK;

Tongxin Zhang, Hong Kong, HK;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/357 (2006.01); C07D 319/08 (2006.01); C07D 493/08 (2006.01); A61K 31/22 (2006.01); C07C 69/18 (2006.01);
U.S. Cl.
CPC ...
A61K 31/357 (2013.01); A61K 31/22 (2013.01); C07C 69/18 (2013.01); C07D 319/08 (2013.01); C07D 493/08 (2013.01); C07C 2603/86 (2017.05);
Abstract

The present invention relates to a group of derivatives synthesized based on the ent-kaurane diterpenoid flexicaulin A and the methods to synthesize such diterpenoid derivatives. In particular, the chemical entities of such synthetic diterpene compounds in the manufacture of a medicament is for the treatment of tumors or cancers.


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