The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2019
Filed:
Jul. 15, 2016
Institut Pasteur, Paris, FR;
Universite Paris Descartes, Paris, FR;
Centre Hospitalier Sainte Anne Paris, Paris, FR;
Institut Gustave-roussy, Villejuif, FR;
Fabrice Bruno Chretien, Paris, FR;
Raphael Gaillard, Paris, FR;
Pierre Rocheteau, Paris, FR;
Olivier Mir, Paris, FR;
UNIVERSITE PARIS DESCARTES, Paris, FR;
CENTRE HOSPITALIER SAINTE ANNE PARIS, Paris, FR;
INSTITUT GUSTAVE-ROUSSY, Villejuif, FR;
INSTITUT PASTEUR, Paris, FR;
Abstract
The present invention relates to the field of muscle regeneration, and more particularly to the replenishment of the in vivo muscle stem cells pool. It more specifically relates to a 5-hydroxytryptamine B1 receptor-stimulating agent, and to a composition comprising said agent, for use as i) a promoter of satellite cells self-renewal and/or differentiation, and/or ii) an agent preventing and/or inhibiting the satellite cells pool exhaustion. The invention further encompasses therapeutic and screening methods.