The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 03, 2019

Filed:

Jan. 25, 2018
Applicants:

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

The Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US);

The Regents of the University of Colorado, a Body Corporate, Denver, CO (US);

Inventors:

Paul Alexander Dayton, Carrboro, NC (US);

Paul Steven Sheeran, Durham, NC (US);

Terry Onichi Matsunaga, Tucson, AZ (US);

Mark A. Borden, Boulder, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 49/22 (2006.01); A61K 41/00 (2006.01); B01J 13/02 (2006.01); A61K 49/00 (2006.01); A61K 47/06 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/51 (2013.01); A61K 9/5123 (2013.01); A61K 9/5192 (2013.01); A61K 41/0028 (2013.01); A61K 47/06 (2013.01); A61K 49/0002 (2013.01); A61K 49/221 (2013.01); A61K 49/223 (2013.01); A61K 49/226 (2013.01); B01J 13/02 (2013.01); A61K 48/00 (2013.01);
Abstract

An acoustically activatable particle of material includes a first substance that includes a component that is a gas 25° C. and atmospheric pressure. A second substance, different from the first substance, encapsulates the first substance to create a droplet or emulsion that is stable at room temperature and atmospheric pressure. At least some of the first substance exists in a gaseous phase at the time of encapsulation of the first substance within the second substance to form a bubble. After formation of the bubble, the bubble is condensed into a liquid phase, which causes the bubble to transform into the droplet or emulsion having a core consisting of a liquid. The droplet or emulsion is an activatable phase change agent having a core consisting of a liquid at 25° C. and atmospheric pressure. The first substance has a boiling point below 25° C. at atmospheric pressure.


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