The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2019
Filed:
Feb. 27, 2015
Applicants:
Oy Medix Biochemica Ab, Espoo, FI;
Dentognostics Gmbh, Jena, DE;
Inventors:
Timo Sorsa, Helsinki, FI;
Dirk-Rolf Gieselmann, Solingen, DE;
Armi Korvuo, Hyvinkää, FI;
Kurt Maier, Berlin, DE;
Päivi Mäntylä, Helsinki, FI;
Ismo Råman, Espoo, FI;
Sinikka Tiisala, Helsinki, FI;
Assignees:
OY MEDIX BIOCHEMICA AB, Espoo, FI;
DENTOGNOSTICS GMBH, Jena, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/573 (2006.01); C12N 9/64 (2006.01); C07K 14/81 (2006.01);
U.S. Cl.
CPC ...
G01N 33/573 (2013.01); C07K 14/8146 (2013.01); C12N 9/64 (2013.01); C12N 9/6491 (2013.01); C12Y 304/24034 (2013.01); G01N 2333/96494 (2013.01); G01N 2800/18 (2013.01); G01N 2800/50 (2013.01);
Abstract
MMP-8 activation products are disclosed that have a MMP-8 middle-part activation product having a size between 20-35 kDa. Methods of detecting the MMP-8 activation product or activated MMP-8 fragments in a biological sample derived from a subject are also disclosed. The MMP-8 activation product or activated MMP-8 fragments diagnose diseases based on abnormal or elevated levels of activated MMP-8.