The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2019
Filed:
Jul. 25, 2017
Methods for treating patients at risk for costimulation blockade resistant rejection with belatacept
Applicant:
Bristol-myers Squibb Company, Princeton, NJ (US);
Inventors:
Allan D Kirk, Durham, NC (US);
Jaclyn Rae Espinosa, Durham, NC (US);
Robert M Townsend, Garnet Valley, PA (US);
Assignee:
BRISTOL-MYERS SQUIBB COMPANY, Princeton, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/569 (2006.01); G01N 33/80 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56972 (2013.01); G01N 2800/245 (2013.01); G01N 2800/52 (2013.01);
Abstract
The present invention provides methods utilizing changes in CD4+CD57+ T cells levels for determining the susceptibility of a transplant patient or patient in need thereof to costimulation blockade resistant rejection. These methods are useful for identifying effective drug regimens for the treatment of immune disorders associated with graft transplantation and/or maintenance of a transplant.