The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2019

Filed:

Mar. 16, 2016
Applicant:

Pacific Biosciences of California, Inc., Menlo Park, CA (US);

Inventors:

Paul Lundquist, San Francisco, CA (US);

Mark McDonald, Milpitas, CA (US);

Aaron Rulison, Los Altos, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/6874 (2018.01); G01N 21/64 (2006.01); G02B 6/30 (2006.01); G02B 6/125 (2006.01); G02B 6/34 (2006.01); G01N 21/77 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); G01N 21/648 (2013.01); G01N 21/6452 (2013.01); G01N 21/7703 (2013.01); G01N 2201/06113 (2013.01); G01N 2201/08 (2013.01); G02B 6/125 (2013.01); G02B 6/30 (2013.01); G02B 6/34 (2013.01);
Abstract

Optical delivery devices and integrated analytical systems comprising the optical delivery devices are provided. The optical delivery devices include optical inputs, optical outputs, and integrated optical waveguides that are configured for coupling of optical energy to a target waveguide device through free space. The integrated analytical systems include the optical delivery devices in combination with the target waveguide device. The devices and systems are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. The devices provide for the efficient coupling of optical excitation energy from an optical source to the optical reactions. Optical signals emitted from the reactions can thus be measured with high sensitivity and discrimination. The devices and systems are well suited for miniaturization and high throughput.


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