The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2019

Filed:

Jul. 10, 2014
Applicant:

Gradientech Ab, Uppsala, SE;

Inventors:

Johan Kreuger, Uppsala, SE;

Sara Thorslund, Uppsala, SE;

Zhigang Wu, Uppsala, SE;

Assignee:

GRADIENTECH AB, Uppsala, SE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/18 (2006.01); C12M 1/16 (2006.01); C12Q 1/02 (2006.01); C12M 3/06 (2006.01); C12M 1/12 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/18 (2013.01); C12M 1/16 (2013.01); C12M 23/16 (2013.01); C12M 25/14 (2013.01); C12Q 1/02 (2013.01); B01L 3/5027 (2013.01);
Abstract

A fluidic device () has a culture chamber () configured to house a 3D culture matrix () comprising a culture of microorganisms (). A concentration gradient of a test substance is established over the 3D culture matrix () by providing respective fluid flows at different end portions () of the culture chamber () and comprising different concentrations of the test substance. The response of the microorganisms () to the test substance is determined based on the position of a border zone () in the 3D culture matrix ().


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