The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2019
Filed:
Jun. 10, 2016
Applicant:
National Research Council of Canada, Ottawa, CA;
Inventors:
Anne E. G. Lenferink, Lorraine, CA;
Maureen D. O'Connor, Beaconsfield, CA;
Anne Marcil, Pierrefonds, CA;
Yves Durocher, Montreal, CA;
Assignee:
National Research Council of Canada, Ottawa, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); A61K 47/68 (2017.01); G01N 33/53 (2006.01); G01N 33/563 (2006.01); G01N 33/574 (2006.01); G01N 33/573 (2006.01); A61K 51/10 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 47/6803 (2017.08); A61K 47/6871 (2017.08); A61K 51/1075 (2013.01); G01N 33/573 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); G01N 2333/988 (2013.01);
Abstract
The present invention relates to isolated or purified antibodies or fragments thereof specific for Carbohydrate Anhydrase IX (CA-IX) and their use as therapeutic tools. Specifically, the present invention is directed to high-affinity Carbohydrate Anhydrase IX-specific antibodies and fragments thereof and their use as antibody-drug conjugates. Compositions for use in therapy as well as therapeutic methods are also described.