The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2019

Filed:

May. 17, 2016
Applicants:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

U.s. Government As Represented BY the Department of Veterns Affairs, Washington, DC (US);

The Regents of the University of California, Oakland, CA (US);

Alkahest, Inc., San Carlos, CA (US);

Inventors:

Anton Wyss-Coray, Palo Alto, CA (US);

Saul A. Villeda, Lancaster, CA (US);

Karoly Nikolich, Redwood City, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61M 1/36 (2006.01); A61P 25/28 (2006.01); C07K 16/28 (2006.01); C12N 15/113 (2010.01); A61K 31/7088 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2833 (2013.01); A61K 31/7088 (2013.01); A61M 1/3621 (2013.01); A61P 25/28 (2018.01); C12N 15/1138 (2013.01); A61M 2202/07 (2013.01); C12N 2310/11 (2013.01); C12N 2310/341 (2013.01);
Abstract

Methods of treating an adult mammal for an aging-associated impairment are provided. Aspects of the methods include reducing the 2-microglobulin (B2M) level in the mammal in a manner sufficient to treat the mammal for the aging-associated impairment. A variety of aging-associated impairments may be treated by practice of the methods, which impairments include cognitive impairments.


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