The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2019

Filed:

Mar. 17, 2017
Applicants:

Virus Ikagaku Kenkyusho Inc., Osaka, JP;

Japan Tobacco Inc., Tokyo, JP;

Inventors:

Kazuhiro Kondo, Tokyo, JP;

Nobuyuki Kobayashi, Tokyo, JP;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/10 (2006.01); C12N 15/63 (2006.01); C12N 15/79 (2006.01); C12N 7/01 (2006.01); C07K 14/005 (2006.01); C07K 14/03 (2006.01); C12N 7/00 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); C07K 14/03 (2013.01); C12N 5/10 (2013.01); C12N 7/00 (2013.01); C12N 15/63 (2013.01); C12N 15/79 (2013.01); G01N 33/6854 (2013.01); G01N 33/6893 (2013.01); G01N 33/6896 (2013.01); A01K 2267/0356 (2013.01); C12N 2710/10343 (2013.01); C12N 2710/16522 (2013.01); C12N 2710/16571 (2013.01); C12N 2740/10043 (2013.01); G01N 2333/035 (2013.01); G01N 2800/304 (2013.01);
Abstract

Disclosed are a protein and a gene each of which is a factor involved in latent infection with a herpesvirus. An antibody against the factor was detected in approximately 50% of patients suffering from mental disorders, whereas the antibody was hardly detected in healthy persons. Further, a mouse having SITH-1 introduced therein developed a mental disorder such as a manic-depressive illness or depression-like disorder. Based on these findings, it is possible to provide a method for objectively determining a mental disorder and an animal model of a mental disorder.


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