The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2019

Filed:

Jul. 06, 2016
Applicant:

Illumina Cambridge Limited, Nr. Saffron Walden, Essex, GB;

Inventors:

Xiaohai Liu, Nr. Saffron Walden, GB;

John Milton, Nr. Saffron Walden, GB;

Silke Ruediger, Nr. Saffron Walden, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/04 (2006.01); C07H 21/00 (2006.01); C12Q 1/68 (2006.01); C12Q 1/6874 (2018.01); C07H 21/04 (2006.01); C07H 19/06 (2006.01); C07H 19/10 (2006.01); C07H 19/16 (2006.01); C07H 19/20 (2006.01); C12Q 1/6869 (2018.01); C07H 19/14 (2006.01);
U.S. Cl.
CPC ...
C07H 19/04 (2013.01); C07H 19/06 (2013.01); C07H 19/10 (2013.01); C07H 19/14 (2013.01); C07H 19/16 (2013.01); C07H 19/20 (2013.01); C07H 21/00 (2013.01); C07H 21/04 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6874 (2013.01); Y10T 436/143333 (2015.01);
Abstract

The invention provides a nucleotide or nucleoside having a base attached to a detectable label via a cleavable linker, characterized in that the cleavable linker contains a moiety selected from the group comprising: Formula (I) (wherein X is selected from the group comprising O, S, NH and NQ wherein Q is a Csubstituted or unsubstituted alkyl group, Y is selected from the group comprising O, S, NH and N(allyl), T is hydrogen or a Csubstituted or unsubstituted alkyl group and * indicates where the moiety is connected to the remainder of the nucleotide or nucleoside).


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