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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10487074 B1

PDFFull Text
Date of Patent:
Nov. 26, 2019

Filed:

Nov. 24, 2016

Method for purifying benzopyran derivative, crystal form thereof, and method for preparing crystal form

Applicant:

Hanlim Pharmaceutical Co., Ltd., Yongin-si, Gyeonggi-do, KR;

Inventors:

Jae-Chun Ryu, Yongin-si, KR;

Yong-Kyun Park, Seongnam-si, KR;

Hyun-Kyu Kim, Gwangmyeong-si, KR;

Dong-Yeop Shin, Gunpo-si, KR;

Assignee:

HANLIM PHARMACEUTICAL CO., LTD., Yongin-si, Gyeonggi-do, KR;

Attorneys:

Vorys, Sater, Seymour & Pease LLP

Mih Suhn Koh

Primary Examiner:

Amanda L Aguirre

Int. Cl.
CPC ...
C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention provides a process for purifying (2R,3R,4S)-6-amino-4-[N-(4-chlorophenyl)-N-(1H-imidazol-2-ylmethyl)amino]-3-hydroxy-2-methyl-2-dimethoxymethyl-3,4-dihydro-2H-1-benzopyran, comprising converting an amorphous (2R,3R,4S)-6-amino-4-[N-(4-chlorophenyl)-N-(1H-imidazol-2-ylmethyl)amino]-3-hydroxy-2-methyl-2-dimethoxymethyl-3,4-dihydro-2H-1-benzopyran to a crystalline form thereof. And also, the present invention provides a novel crystalline form of (2R,3R,4S)-6-amino-4-[N-(4-chlorophenyl)-N-(1H-imidazol-2-ylmethyl)amino]-3-hydroxy-2-methyl-2-dimethoxymethyl-3,4-dihydro-2H-1-benzopyran and processes for preparing the same.

Find Patent Forward Citations

Ryu, Jae-Chun. (2019). Method for purifying benzopyran derivative, crystal form thereof, and method for preparing crystal form (U.S. Patent No. 10487074). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10487074

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