The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2019
Filed:
Sep. 24, 2018
Applicant:
Apotex Inc., Toronto, CA;
Inventors:
Fabio E. S. Souza, Mississauga, CA;
Bahareh Khalili, Mississauga, CA;
Annyt Bhattacharyya, Hamilton, CA;
Assignee:
Apotex Inc., Toronto, Ontario, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 233/64 (2006.01); A61P 1/12 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
C07D 233/64 (2013.01); A61K 9/20 (2013.01); A61P 1/12 (2018.01); C07B 2200/13 (2013.01);
Abstract
The present invention provides a novel crystalline form of Eluxadoline, Eluxadoline Form APO-I, a co-crystal of Eluxadoline and methyl nicotinate, compositions and processes for the preparation thereof, and the use of this crystalline form in the treatment of opioid-modulated disorders, and in particular, gastrointestinal disorders, including irritable bowel syndrome with diarrhea (IBS-D).