The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2019

Filed:

Mar. 05, 2015
Applicants:

Kewpie Corporation, Tokyo, JP;

University of Tsukuba, Tsukuba-shi, JP;

Inventors:

Hideyoshi Harashima, Sapporo, JP;

Mamoru Hyodo, Sapporo, JP;

Naoyuki Toriyabe, Sapporo, JP;

Nobuhiro Ohkohchi, Tsukuba, JP;

Takafumi Tamura, Tsukuba, JP;

Naoki Sano, Tsukuba, JP;

Assignees:

Kewpie Corporation, Tokyo, JP;

University of Tsukuba, Tsukuba-shi, JP;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/61 (2017.01); A61K 47/36 (2006.01); A61K 31/661 (2006.01); C08B 37/08 (2006.01); C08L 5/08 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/36 (2013.01); A61K 9/0019 (2013.01); A61K 31/661 (2013.01); A61K 47/61 (2017.08); C08B 37/0072 (2013.01); C08L 5/08 (2013.01);
Abstract

Hyaluronic acid modified with sphingosine-1-phosphate, and a medicine comprising the hyaluronic acid as an active ingredient, wherein the medicine can alleviate hepatic disorder caused by hypoxia/reoxygenation by protecting the liver sinusoidal endothelial cells, and the medicine can prevent and/or treat liver failure due to liver transplantation, hepatectomy, or other surgeries associated with liver ischemia/reperfusion.


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