The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2019

Filed:

Sep. 25, 2017
Applicants:

International Business Machines Corporation, Armonk, NY (US);

Nanomalaysia Berhad, Kuala Lumpur, MY;

Inventors:

Khairiah H. Badri, Bandar Baru Bangi, MY;

Emilia B. A. Malek, Selangor, MY;

Siti Mariam B. Mohd Nor, Seri Kembangan, MY;

Victoria A. Piunova, Los Gatos, CA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/34 (2017.01); A61K 47/10 (2017.01); A61K 47/60 (2017.01); A61K 31/00 (2006.01); C08F 293/00 (2006.01); A61K 8/34 (2006.01); A61Q 19/00 (2006.01); A61K 8/91 (2006.01); A61K 9/00 (2006.01); A61Q 17/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/34 (2013.01); A61K 8/347 (2013.01); A61K 8/91 (2013.01); A61K 31/00 (2013.01); A61K 47/10 (2013.01); A61K 47/60 (2017.08); A61Q 19/00 (2013.01); C08F 293/00 (2013.01); A61K 9/00 (2013.01); A61K 2800/10 (2013.01); A61K 2800/544 (2013.01); A61Q 17/005 (2013.01);
Abstract

Mikto-arm star polymers were prepared comprising non-charged hydrophilic poly(ethylene oxide) arms and hydrophobic arms comprising a poly(propylene oxide) chain or phytol group. The polymer arms are covalently linked to a hydrophobic crosslinked polyester core formed by ring opening polymerization of a bis-cyclic ester initiated by mono-nucleophilic polymer arm precursors. The mikto-arm star polymers show improved loading capacity for Coenzyme Q10 (CoQ10).


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