The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2019
Filed:
Sep. 19, 2017
Applicant:
Taipei Medical University, Taipei, TW;
Inventors:
Jaulang Hwang, Taipei, TW;
Chung-Ming Chen, Taipei, TW;
Assignee:
TAIPEI MEDICAL UNIVERSITY, Taipei, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61P 11/00 (2006.01); A61K 47/64 (2017.01); C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39558 (2013.01); A61K 47/646 (2017.08); A61P 11/00 (2018.01); C07K 16/241 (2013.01);
Abstract
The present invention develops a vaccine composition against and treatment or prevention on inflammation and lung injury (particularly hyperoxia-induced lung injury) and progression of periodontitis. Tn immunization increases serum anti-Tn antibody titers, while it decreases lavaged protein and cytokines, and also decreases mean linear intercept and lung injury score. Furthermore, the improvement in lung injury is accompanied by a decrease in NF-κB activity.