The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2019
Filed:
Oct. 06, 2015
Applicant:
Serum Institute of India Private Limited, Maharashtra, Pune, IN;
Inventors:
Rajeev Mhalasakant Dhere, Pune, IN;
Sambhaji Shankar Pisal, Pune, IN;
Jagdish Kamalaji Zade, Pune, IN;
Rajendra Narayan Sabale, Pune, IN;
Assignee:
SERUM INSTITUTE OF INDIA PVT LTD, Maharashtra Pune, IN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/13 (2006.01); A61K 39/39 (2006.01); C12N 7/06 (2006.01); C12N 7/04 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/13 (2013.01); A61K 39/39 (2013.01); C12N 7/00 (2013.01); C12N 7/045 (2013.01); C12N 7/06 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/575 (2013.01); A61K 2039/70 (2013.01); C12N 2770/32334 (2013.01); C12N 2770/32634 (2013.01); C12N 2770/32663 (2013.01); C12N 2770/32671 (2013.01); Y02A 50/383 (2018.01); Y02A 50/386 (2018.01); Y02A 50/388 (2018.01); Y02A 50/39 (2018.01); Y02A 50/392 (2018.01); Y02A 50/412 (2018.01); Y02A 50/466 (2018.01); Y02A 50/484 (2018.01);
Abstract
The present invention is directed to improved methods of Enterovirus inactivation by formaldehyde in presence of tromethamine buffer resulting in maximum recovery of D-antigen. Subsequent adsorption of said sIPV on aluminium hydroxide provides significantly dose reduced sIPV compositions.