The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2019

Filed:

Apr. 05, 2017
Applicant:

Boehringer Ingelheim Animal Health Usa Inc., Duluth, GA (US);

Inventors:

Laurent Fischer, Sainte Foy les Lyon, FR;

Yovany Moreno, Alpharetta, GA (US);

Cecile Sigoillot-Claude, Ouillins, FR;

Frederic Beugnet, Thurins, FR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07H 21/04 (2006.01); A61K 39/002 (2006.01); C07K 16/20 (2006.01); A61K 39/02 (2006.01); C07K 14/435 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0003 (2013.01); A61K 39/0233 (2013.01); C07K 14/4354 (2013.01); C07K 16/20 (2013.01); C07K 14/43536 (2013.01);
Abstract

The present invention encompasses a vaccine composition and method of use for treating heartworm infestation in mammals. The vaccine composition includes chimeric antigens engineered and manufactured using the genetic code (i.e., the amino acid or protein sequence) of the target sequence. After introduction of the vaccine composition containing the target antigen into the host (e.g., a canine), the host will generate antibodies as part of its robust immune response to the antigen. As the antibodies circulate through the host's plasma, heartworm larvae will consume the antibodies as they feed on the plasma. The antibodies will then act on internal targets of the worm recognized as antigens.


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