The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2019

Filed:

Jul. 25, 2016
Applicant:

Oregon Health & Science University, Portland, OR (US);

Inventors:

David Huang, Portland, OR (US);

Yali Jia, Portland, OR (US);

Jason Tokayer, Visalia, CA (US);

Ou Tan, Portland, OR (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 3/10 (2006.01); A61B 3/12 (2006.01); A61B 5/026 (2006.01); A61B 5/0205 (2006.01); A61B 5/00 (2006.01); G06T 7/00 (2017.01); A61B 3/00 (2006.01); G01B 9/02 (2006.01);
U.S. Cl.
CPC ...
A61B 3/1241 (2013.01); A61B 3/0025 (2013.01); A61B 3/102 (2013.01); A61B 5/0066 (2013.01); A61B 5/0205 (2013.01); A61B 5/0261 (2013.01); A61B 5/7207 (2013.01); A61B 5/7246 (2013.01); A61B 5/7278 (2013.01); G01B 9/02004 (2013.01); G01B 9/02044 (2013.01); G01B 9/02091 (2013.01); G06T 7/0016 (2013.01); A61B 5/7203 (2013.01); A61B 2576/02 (2013.01); G06T 2207/10101 (2013.01); G06T 2207/30041 (2013.01); G06T 2207/30104 (2013.01);
Abstract

Impaired intraocular blood flow within vascular beds in the human eye is associated with certain ocular diseases including, for example, glaucoma, diabetic retinopathy and age-related macular degeneration. A reliable method to quantify blood flow in the various intraocular vascular beds could provide insight into the vascular component of ocular disease pathophysiology. Using ultrahigh-speed optical coherence tomography (OCT), a new 3D angiography algorithm called split-spectrum amplitude-decorrelation angiography (SSADA) was developed for imaging microcirculation within different intraocular regions. A method to quantify SSADA results was developed and used to detect perfusion changes in early stage ocular disease. Associated embodiments relating to methods for quantitatively measuring blood flow at various intraocular vasculature sites, systems for practicing such methods, and use of such methods and systems for diagnosing certain ocular diseases are herein described.


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