The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 19, 2019

Filed:

Mar. 26, 2013
Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Arthur C. Hewig, III, Newbury Park, CA (US);

Duke H. Phan, Kenmore, WA (US);

Yinges Yigzaw, Issaquah, WA (US);

Robert Bailey, Bothell, WA (US);

Assignee:

AMGEN INC., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C07K 16/00 (2006.01); C07K 16/06 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6854 (2013.01); C07K 16/00 (2013.01); C07K 16/065 (2013.01);
Abstract

The invention provides a method for controlling contaminants in biopharmaceutical purification processes by using light scattering and UV absorbance to establish a determinant. The invention makes use of multi-angle light scattering (MALS) and UV as a continuous monitoring system to provide information about the elution peak fractions in real-time instead of conventional pooling methods that rely on a predetermined percent UV peak max value to initiate the pooling process; regardless of product quality.


Find Patent Forward Citations

Hewig, III, Arthur. (2019). Method for using light scattering in real time to directly monitor and control impurity removal in purification processes (U.S. Patent No. 10481164). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10481164

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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