The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 19, 2019

Filed:

Jan. 14, 2016
Applicants:

Ohio State Innovation Foundation, Columbus, OH (US);

University of Freiburg, Freiburg, DE;

Inventors:

Arnab Chakravarti, Dublin, OH (US);

Erica McKenzie Bell, Columbus, OH (US);

Simon Kirste, Freiburg, DE;

Anca-Ligia Grosu, Freiburg, DE;

Assignees:

Ohio State Innovation Foundation, Columbus, OH (US);

University of Freiburg, Freiburg, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/11 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12Q 1/6886 (2018.01); G16B 25/00 (2019.01); G16B 40/00 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); G16B 25/00 (2019.02); G16B 40/00 (2019.02); C12Q 2600/106 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01);
Abstract

The lack of clear predictors of prostate cancer progression leads to subjective decision-making regarding courses of treatment. The identification of new biomarkers that are predictive of recurrence after radical prostatectomy would advance the field of prostate cancer treatment. Disclosed are miRNAs that can be used as molecular biomarkers to detect or predict the progression of prostate cancer and to adjust a treatment plan accordingly. Furthermore, kits are included for the detection of these miRNAs.


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