The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2019
Filed:
Jan. 28, 2016
Applicant:
Northwestern University, Evanston, IL (US);
Inventors:
Monica M. Laronda, Chicago, IL (US);
Alexandra L. Rutz, Chicago, IL (US);
Ramille N. Shah, Hinsdale, IL (US);
Teresa K. Woodruff, Chicago, IL (US);
Assignee:
NORTHWESTERN UNIVERSITY, Evanston, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); C12N 5/075 (2010.01); A61K 35/54 (2015.01); B33Y 80/00 (2015.01); B33Y 70/00 (2015.01); B29C 64/106 (2017.01); B29L 31/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0697 (2013.01); A61K 35/54 (2013.01); B29C 64/106 (2017.08); B33Y 70/00 (2014.12); B33Y 80/00 (2014.12); C12N 5/0609 (2013.01); C12N 5/0682 (2013.01); B29K 2089/00 (2013.01); B29L 2031/7532 (2013.01); C12N 2502/04 (2013.01); C12N 2502/243 (2013.01); C12N 2513/00 (2013.01); C12N 2533/54 (2013.01); C12N 2533/90 (2013.01); C12N 2537/10 (2013.01);
Abstract
Artificial ovaries comprising porous three-dimensional scaffolds are provided. Also provided are ink compositions and methods for printing the scaffolds. The artificial ovaries have spatial arrangements and cellular compositions that allow them to mimic native ovarian tissue. As such, they can be cultured or transplanted to support female endocrine function and/or the development of oocytes and/or eggs.