The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 19, 2019

Filed:

Jun. 17, 2016
Applicants:

Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;

F. Hoffmann-la Roche Ag, Basel, CH;

Inventors:

Hirosato Ebiike, Kanagawa, JP;

Toshihiro Aoki, Kanagawa, JP;

Takashi Chiba, Kanagawa, JP;

Masami Kochi, Kanagawa, JP;

Kimitaka Nakama, Kanagawa, JP;

Satoshi Niizuma, Shizuoka, JP;

Hiroki Nishii, Kanagawa, JP;

Jun Ohwada, Tokyo, JP;

Hiroyuki Shimamura, Kanagawa, JP;

Aiko Suge, Shizuoka, JP;

Yoshito Nakanishi, Kanagawa, JP;

Natsuki Kobayashi, Kanagawa, JP;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/06 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/06 (2013.01); C07D 401/14 (2013.01);
Abstract

An objective of the present invention is to provide low-molecular-weight compounds that can inhibit Src family kinases. The present invention relates to compounds represented by general formula (I) or pharmacologically acceptable salts thereof. In the formula, Aris optionally substituted Carylene or 5- to 10-membered heteroarylene, and Aris optionally substituted Caryl or 5- to 10-membered heteroaryl. Rand Rare defined as described in the specification.


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