The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2019
Filed:
Feb. 15, 2016
Amorepacific Corporation, Seoul, KR;
Byoung Young Woo, Yongin-si, KR;
Ki-Wha Lee, Yongin-si, KR;
Kwang-Hyun Shin, Yongin-si, KR;
Miyoung Park, Yongin-si, KR;
Kyoungmi Jung, Yongin-si, KR;
Joonho Choi, Yongin-si, KR;
Gyeyoung Choi, Yongin-si, KR;
Wonkyung Cho, Yongin-si, KR;
Young-Ho Park, Yongin-si, KR;
AMOREPACIFIC CORPORATION, Seoul, KR;
Abstract
The present specification relates to a chiral resolution method of a stereoisomer mixture, comprising a step of mixing a stereoisomer mixture of compounds, in which an amine group is bound to an asymmetric carbon atom, with a chiral auxiliary and salt-forming auxiliary compound, wherein the chiral auxiliary is an O,O'-diacyltartaric acid derivative, more specifically, a 2,3-dibenzoyl-tartaric acid or O,O′-di-p-toluoyl tartaric acid, the salt-forming auxiliary compound is mandelic acid or camphorsulfonic acid, and an optical isomer having a high level of optical purity can be obtained by using the method. Therefore, according to one aspect of the present invention, the method can be useful in pharmaceutical or cosmetic field when preparing an optical isomer having a high optical purity.