The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2019
Filed:
Aug. 19, 2016
Applicants:
University of Rochester, Rochester, NY (US);
Cornell University, Ithaca, NY (US);
Inventors:
Luis Martinez-Sobrido, Rochester, NY (US);
Aitor Nogales-Gonzalez, Rochester, NY (US);
Colin Parrish, Ithaca, NY (US);
Assignees:
University of Rochester, Rochester, NY (US);
Cornell University, Ithaca, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/145 (2006.01); A61P 31/16 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/145 (2013.01); A61P 31/16 (2018.01); A61K 2039/5254 (2013.01); A61K 2039/543 (2013.01); A61K 2039/552 (2013.01); A61K 2039/58 (2013.01);
Abstract
The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that various mutations in segment 1 and segment 2 of the CIV genome, thereby encoding mutant PB2 and PB1 protein, render the virus to be temperature-sensitive.