The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2019
Filed:
Jun. 10, 2016
Applicant:
Nestec S.a., Vevey, CH;
Inventors:
Sophie Helene Nutten, Palezieux-village, CH;
Nanda De Groot, Pully, CH;
Valerie Francoise Verhasselt, Vallauris, FR;
Assignee:
Societe des Produits Nestle S.A., Vevey, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A23L 33/00 (2016.01); A23L 33/17 (2016.01); A23K 20/147 (2016.01); A23K 50/40 (2016.01); A23K 50/60 (2016.01); A61K 38/01 (2006.01); A23L 33/18 (2016.01); A61P 37/08 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1841 (2013.01); A23K 20/147 (2016.05); A23K 50/40 (2016.05); A23K 50/60 (2016.05); A23L 33/17 (2016.08); A23L 33/18 (2016.08); A23L 33/40 (2016.08); A61K 38/018 (2013.01); A61P 37/08 (2018.01); A23V 2002/00 (2013.01);
Abstract
This invention relates to the administration of a combination of TGF-β and one or more peptides comprising specific sequences of β-lacto-globulin. The peptides are hypoallergenic but retain the capability to induce tolerance to the native protein. The combination of TGF-β and one or more of these peptides has the therapeutic effect of inducing and maintaining oral tolerance towards newly introduced proteins, in particular, at the weaning period. The combination can modulate the infant and toddler immune response to allergens.