The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2019
Filed:
Apr. 18, 2018
Buck Institute for Research on Aging, Novato, CA (US);
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Unity Biotechnology, Inc., Brisbane, CA (US);
Remi-Martin Laberge, San Francisco, CA (US);
Judith Campisi, Berkeley, CA (US);
Marco Demaria, Groningen, NL;
Nathaniel David, Brisbane, CA (US);
Alain Philippe Vasserot, Carlsbad, CA (US);
James L. Kirkland, Rochester, MN (US);
Tamar Tchkonia, Rochester, MN (US);
Yi Zhu, Rochester, MN (US);
Darren J. Baker, Rochester, MN (US);
Bennett G. Childs, Rochester, MN (US);
Jan M. A. van Deursen, Rochester, MN (US);
Unity Biotechnology, Inc., Brisbane, CA (US);
Buck Institute for Research on Aging, Novato, CA (US);
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Abstract
Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic agent. Senescence-associated diseases and disorders treatable by the methods using the senolytic agents described herein include cardiovascular diseases and disorders associated with or caused by arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease; osteoarthritis; senescence-associated ophthalmic diseases and disorders; and senescence-associated dermatological diseases and disorders.