The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2019
Filed:
May. 13, 2019
Academia Sinica, Taipei, TW;
An-Suei Yang, Emeryville, CA (US);
Hong-Sen Chen, Taipei, TW;
Ing-Chien Chen, Taipei, TW;
Chao-Ping Tung, Taipei, TW;
Shin-Chen Hou, Taipei, TW;
Chung-Ming Yu, Taipei, TW;
Chi-Kai Yang, Taipei, TW;
Yi-Kai Chiu, Taipei, TW;
Academia Sinica, Taipei, TW;
Abstract
Disclosed herein is a phage-displayed single-chain variable fragment (scFv) library, that comprised a plurality of phage-displayed scFvs characterized with (1) a specific CS combination; (2) a specific distribution of aromatic residues in each CDR; and (3) a specific sequence in each CDR. The present scFv library could be used to efficiently produce different antibodies with binding affinity to different antigens. Accordingly, the present disclosure provides a potential means to generate different antigen-specific antibodies promptly in accordance with the need in experimental researches and/or clinical applications.