The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2019
Filed:
Dec. 08, 2016
Applicant:
Cancer Research Technology Limited, London, GB;
Inventors:
Joerg Bartsch, London, GB;
Garrit Koller, London, GB;
Assignees:
CANCER RESEARCH TECHNOLOGY LIMITED, London, GB;
KING'S COLLEGE LONDON, London, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 4/00 (2006.01); C07K 5/00 (2006.01); C07K 5/12 (2006.01); C07K 7/64 (2006.01); A61K 38/03 (2006.01); A61K 38/12 (2006.01); C07K 7/56 (2006.01); A61K 38/00 (2006.01); C07K 5/02 (2006.01); C07K 14/81 (2006.01); C12N 9/64 (2006.01); C07K 7/06 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
C07K 7/56 (2013.01); A61K 38/005 (2013.01); A61K 38/12 (2013.01); C07K 5/0202 (2013.01); C07K 5/12 (2013.01); C07K 5/123 (2013.01); C07K 5/126 (2013.01); C07K 7/06 (2013.01); C07K 7/64 (2013.01); C07K 14/8146 (2013.01); C07K 16/40 (2013.01); C12N 9/6489 (2013.01); C12Y 304/24046 (2013.01); A61K 38/00 (2013.01); C07K 2317/76 (2013.01);
Abstract
The invention relates to a method for inhibiting an ADAM protease, comprising inhibiting binding to an integrin-binding loop of a disintegrin domain in the ADAM protease. Also provided are cyclic peptides which inhibit binding to an integrin-binding loop of an ADAM protease, as well as associated pharmaceutical compositions, uses and methods of treatment.