The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2019
Filed:
Mar. 01, 2017
Applicant:
Shanghai Allist Pharmaceuticals, Inc., Shanghai, CN;
Inventors:
Huibing Luo, Shanghai, CN;
Huayong Zhou, Shanghai, CN;
Assignee:
SHANGHAI ALLIST PHARMACEUTICAL AND MEDICAL TECH CO, Shanghai, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61P 35/00 (2006.01); A61K 31/506 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/506 (2013.01); A61P 35/00 (2018.01);
Abstract
A mesylate salt of the compound of formula (I), the preparation method thereof, a pharmaceutical composition containing said salt and the use of said salt in treating diseases mediated by activating and resistance mutations of EGFR, in particular cancers, in mammal, in particular human. The mesylate salt of the compound of formula (I) has a high bioavailability in animal, and can remarkably inhibit the growth of transplanted tumors in animal and show a good safety.