The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2019
Filed:
Oct. 30, 2015
The General Hospital Coporation, Boston, MA (US);
The Regents of the University of California, Oakland, CA (US);
Steven L. Wagner, San Diego, CA (US);
William C. Mobley, La Jolla, CA (US);
Rudolph E. Tanzi, Hull, MA (US);
Graham Johnson, Sanbornton, NH (US);
Ronald Buckle, Delmar, NY (US);
Nicholas Mayhew, Niskayuna, NY (US);
Robert Jason Herr, Voorheesville, NY (US);
Steven L. Wagner, San Diego, CA (US);
William C. Mobley, La Jolla, CA (US);
Rudolph E. Tanzi, Hull, MA (US);
Graham Johnson, Sanbornton, NH (US);
Ronald Buckle, Delmar, NY (US);
Nicholas Mayhew, Niskayuna, NY (US);
Robert Jason Herr, Voorheesville, NY (US);
Kevin D. Rynearson, La Mesa, CA (US);
The General Hospital Corporation, Boston, MA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
Provided herein are compounds and methods for treating a disorder associated with aberrant A3 peptide levels, including Alzheimer's disease. Provided herein are compositions and methods for treating a disorder associated with aberrant Aβ peptide levels, including AD. Provided herein are compounds of Formula (A) or a pharmaceutically acceptable salt thereof, wherein, L' is selected from the group consisting of C(O), C(R1)(R2), substituted or unsubstituted —C2-6 alkylene-, and substituted or unsubstituted —C3-6 cycloalkylene.